Ozempic's Hidden Costs: Hair, Skin, and Confidence | Image Source: www.verywellhealth.com
INDIANAPOLIS, Indiana, 4 April 2025 - Weight loss medications like Ozempic (semaglutide) have taken the world by storm, widely acclaimed for their impressive ability to help people lose pounds quickly. However, under the surface of the most frightening figures and reduced size, a less known set of side effects is beginning to attract public attention and concern. From accelerated hair loss and fragile acne eruptions and the “ocean face” thus discussed, aesthetic cuts lead to a more in-depth discussion of what we sacrifice in the name of rapid transformation.
Although many are heading to Ozempic for their promise of quick results, doctors are beginning to see patients with cosmetic changes that have not anticipated. These physical changes, often visible and emotional, raise questions from patients and physicians: Is the cost of rapid weight loss higher than we think? What can be done to prevent or reverse these results?
What is “the ozempic face” and why?
“Ocempic Face” has become a word of viral buzz through TikTok and Instagram. Joined by dermatologists and aesthetic doctors, he describes hollow cheeks, draconian jowls, and the appearance of the aged skin some individuals live after dramatic weight loss, especially with GLP-1 agonists such as Ozempic, Wegovy and Zepbound.
According to Dr Judey Pretorius, founder of Biomedical Emporium, is mainly driven by rapid loss of facial fat. “Facial fat plays a protective role. When lost quickly, the skin can’t bounce, which leads to a rebound,” he explains. According to Harvard Health Publishing, sudden weight loss does not allow the skin enough time to adapt to the new body shape, especially on the face, where elasticity is the key for young people.
Visible changes include:
- Sunken cheeks
- Loose skin around the jawline
- More prominent wrinkles
- A generally older, tired appearance
These symptoms are not potentially fatal, but for people who strive to feel better in their bodies, cosmetic tolls can be deeply disturbing. The goal is to shine, not look at glove.
What is the frequency of hair loss after weight loss?
Hair thinning is another side effect that is not reported to be rapid weight loss. As WISH-TV reported, many people undergo a remarkable haircut, often three to four months after starting a weight loss diet. Kait Richardson, a registered nutritionist, NDR, explains that this condition, known as telogen effluent, is generally temporary and triggered by physical stressors, including rapid fat loss and dietary changes.
“I always recommend first checking thyroid function,” advises Richardson, noting that hormonal imbalances can also play a role. In a study that included 112 women after manga gastric surgery, nearly 75% experienced a certain level of hair loss. Similar trends are observed in people with LPG-1 such as Ozempic.
And why? It is often a lack of essential nutrients:
- Protein
- Zinc
- Iron
- Vitamin D
- Selenium
- Omega-3 fatty acids
Richardson recommends a simple blood test to identify nutritional deficiencies and create a well rounded and condensed nutrient feeding plan to support hair growth. Fortunately, most people see their hair come back within six months – if they address the underlying health problems.
BPL-1 Drugs and acne link: What’s up?
Another unexpected and emerging consequence in clinical settings is acne. According to a retrospective study in Verywell Health, people using GLP-1 drugs such as Saxenda, Wegovy or Zebound were 34% more likely to develop acne within one year of use. The data, which analysed more than 162,000 patients, showed a more pronounced effect on women, who were 53% more likely to undergo disintegration than their male counterparts.
Stan Tolkachjov, the main author of the study, finds these findings disconcerting. “Typically, weight loss improves hormonal balance. So we expected less acne, no more,” he said. But this was not what the data showed, suggesting a more complex relationship between weight loss drugs and skin health.
Why Might Acne Flare After Weight Loss?
There are several theories. First, weight loss can change hormone levels. In men, weight loss often increases testosterone. In women, testosterone is generally reduced, but change may temporarily interrupt hormonal balance. At the same time, users of GPL-1 tend to have high rates of insulin-like growth factor 1 (IGF-1), a hormone associated with the excessive production of sebo and acne in women.
According to physician Anthony Rossi, dermatologist Memorial Sloan Kettering, GLP-1 drugs also improve insulin sensitivity and reduce systemic inflammation, both should help acne. “But the body does not always respond linearly. Sometimes the initial adjustment period can throw things out of balance,” he said.
Diet, high stress or even prolonged procedures, especially under hypotensive anesthesia, can contribute to skin problems. Thus, while GLP-1 drugs cannot directly cause acne, physiological changes in rapid weight loss cascade could create the perfect storm for disintegration.
What about “ozepic feet” and nail changes?
Although less discussed, there is growing interest in another side effect, called “oepic feet”. As Dr. Esho pointed out, this term refers to discomfort of the feet and structural changes after significant weight loss. The theory is simple: when people lose weight, fat filling under their feet can decrease, leading to pain during walking or exercise.
This change could go unnoticed at first. As the doctor says. Esho, “Patients often do not connect their standing discomfort to their weight loss journey.” But for some, this can affect quality of life and levels of physical activity.
Nail changes, such as fragility and asphyxia, are also common. They are often linked to the same nutritional deficiencies that cause hair thinning, making it a sign that the body can be under stress.
Frequently asked questions
Can I prevent Ozempic face?
Yes, weight loss is the key. Aim to lose 1-2 pounds a week. Force training can help preserve muscle mass and facial volume. Stay hydrated, eat foods that stimulate colageno, and consider using skin care products with hyaluronic acid and peptides. For more advanced cases, skin filling or non-surgical stretching treatments can help.
Will my hair grow back?
In most cases, yes. Hair loss due to rapid weight loss is often temporary. A nutrient-rich diet, along with supplements if necessary, can speed up recovery. Check iron, zinc and vitamin D deficiencies and avoid reducing calories.
Is acne from GLP-1 medications permanent?
Unlikely. Acne may result from hormonal fluctuations or increases in IGF-1. It is generally reduced as the body adapts. For current cases, dermatologists may prescribe oral contraceptives, spironolactone or other systemic acne treatments. Do not stop your medicine without medical advice.
How can I tell if my skin issues are due to weight loss drugs?
There is no definitive evidence, but time is important. If symptoms occur within three to six months of starting treatment, this is an indication. Consult a dermatologist or endocrinologist for a specific assessment. Hormonal and nutritious panels can be clearer.
Are the benefits of Ozempic still worth it?
For many, yes. The ability of the drug to improve glycaemic control, reduce cardiovascular risk and support prolonged weight loss makes it very beneficial. But it is important to manage expectations and be proactive about side effects. Think of it as a holistic transformation, not just a number on a scale.
Management of aesthetic adverse reactions: What you can do
If you are concerned about the visual effects of rapid weight loss, several interventions can help. Beyond feeding and exercise, aesthetic treatments such as Ultherapy, Microneedling and Sculptra injections can restore elasticity and volume. They are better discussed with a dermatologist familiar with patients after the loss of pesos.
Dr. Tolkachjov stressed that there is no need to choose between health and appearance. “Patients do not need to suffer in silence. With the right support, you can have both weight loss and healthy skin,” he said. The goal is not perfection, it is balance.
Ultimately, the increase in GLP-1 drugs marks a turning point in the fight against obesity. But like any powerful tool, they come with nuances that require attention. As more people share their journey, and more data is available, our understanding will deepen. Until then, it is essential to stay informed, listen to your body and associate with health professionals who see the whole situation.
